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The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides a...

The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5226b086e49e4490b45db13401c5d207

The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence

About this item

Full title

The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence

Publisher

England: eLife Sciences Publications, Ltd

Journal title

eLife, 2023-04, Vol.12

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

Antimicrobial peptides (AMPs) offer a promising solution to the antibiotic resistance crisis. However, an unresolved serious concern is that the evolution of resistance to therapeutic AMPs may generate cross-resistance to host AMPs, compromising a cornerstone of the innate immune response. We systematically tested this hypothesis using globally dis...

Alternative Titles

Full title

The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5226b086e49e4490b45db13401c5d207

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5226b086e49e4490b45db13401c5d207

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.84395

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