3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
About this item
Full title
Author / Creator
Wang, Hongbing , Brown, Paul C. , Chow, Edwin C.Y. , Ewart, Lorna , Ferguson, Stephen S. , Fitzpatrick, Suzanne , Freedman, Benjamin S. , Guo, Grace L. , Hedrich, William , Heyward, Scott , Hickman, James , Isoherranen, Nina , Li, Albert P. , Liu, Qi , Mumenthaler, Shannon M. , Polli, James , Proctor, William R. , Ribeiro, Alexandre , Wang, Jian‐Ying , Wange, Ronald L. and Huang, Shiew‐Mei
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Nonclinical testing has served as a foundation for evaluating potential risks and effectiveness of investigational new drugs in humans. However, the current two‐dimensional (2D) in vitro cell culture systems cannot accurately depict and simulate the rich environment and complex processes observed in vivo, whereas animal studies present significant...
Alternative Titles
Full title
3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
Authors, Artists and Contributors
Author / Creator
Brown, Paul C.
Chow, Edwin C.Y.
Ewart, Lorna
Ferguson, Stephen S.
Fitzpatrick, Suzanne
Freedman, Benjamin S.
Guo, Grace L.
Hedrich, William
Heyward, Scott
Hickman, James
Isoherranen, Nina
Li, Albert P.
Liu, Qi
Mumenthaler, Shannon M.
Polli, James
Proctor, William R.
Ribeiro, Alexandre
Wang, Jian‐Ying
Wange, Ronald L.
Huang, Shiew‐Mei
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_523a044f71fe468699fe3793345748a3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_523a044f71fe468699fe3793345748a3
Other Identifiers
ISSN
1752-8054
E-ISSN
1752-8062
DOI
10.1111/cts.13066
