Immune checkpoints are predominantly co-expressed by clonally expanded CD4 + FoxP3 + intratumoral T-...
Immune checkpoints are predominantly co-expressed by clonally expanded CD4 + FoxP3 + intratumoral T-cells in primary human cancers
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Full title
Author / Creator
Bredel, Delphine , Tihic, Edi , Mouraud, Séverine , Danlos, François-Xavier , Susini, Sandrine , Aglave, Marine , Alfaro, Alexia , Mohamed-Djalim, Chifaou , Rouanne, Mathieu , Halse, Héloise , Bigorgne, Amélie , Tselikas, Lambros , Dalle, Stéphane , Hartl, Dana M , Baudin, Eric , Guettier, Catherine , Vibert, Eric , Rosmorduc, Olivier , Robert, Caroline , Ferlicot, Sophie , Parier, Bastien , Albiges, Laurence , de Montpreville, Vincent Thomas , Besse, Benjamin , Mercier, Olaf , Even, Caroline , Breuskin, Ingrid , Classe, Marion , Radulescu, Camélia , Lebret, Thierry , Pautier, Patricia , Gouy, Sébastien , Scoazec, Jean-Yves , Zitvogel, Laurence , Marabelle, Aurélien and Bonvalet, Mélodie
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
In addition to anti-PD(L)1, anti-CTLA-4 and anti-LAG-3, novel immune checkpoint proteins (ICP)-targeted antibodies have recently failed to demonstrate significant efficacy in clinical trials. In these trials, patients were enrolled without screening for drug target expression. Although these novel ICP-targeted antibodies were expected to stimulate...
Alternative Titles
Full title
Immune checkpoints are predominantly co-expressed by clonally expanded CD4 + FoxP3 + intratumoral T-cells in primary human cancers
Authors, Artists and Contributors
Author / Creator
Tihic, Edi
Mouraud, Séverine
Danlos, François-Xavier
Susini, Sandrine
Aglave, Marine
Alfaro, Alexia
Mohamed-Djalim, Chifaou
Rouanne, Mathieu
Halse, Héloise
Bigorgne, Amélie
Tselikas, Lambros
Dalle, Stéphane
Hartl, Dana M
Baudin, Eric
Guettier, Catherine
Vibert, Eric
Rosmorduc, Olivier
Robert, Caroline
Ferlicot, Sophie
Parier, Bastien
Albiges, Laurence
de Montpreville, Vincent Thomas
Besse, Benjamin
Mercier, Olaf
Even, Caroline
Breuskin, Ingrid
Classe, Marion
Radulescu, Camélia
Lebret, Thierry
Pautier, Patricia
Gouy, Sébastien
Scoazec, Jean-Yves
Zitvogel, Laurence
Marabelle, Aurélien
Bonvalet, Mélodie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_52536a48956445e0b8dee1144f166f82
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52536a48956445e0b8dee1144f166f82
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-023-02897-6
