Preserving the Integrity of Liposomes Prepared by Ethanol Injection upon Freeze-Drying: Insights fro...
Preserving the Integrity of Liposomes Prepared by Ethanol Injection upon Freeze-Drying: Insights from Combined Molecular Dynamics Simulations and Experimental Data
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MDPI
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Language
English
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MDPI
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The freeze-drying of complex formulations, such as liposomes, is challenging, particularly if dispersions contain residual organic solvents. This work aimed to investigate the effects of possible protectants, namely sucrose, trehalose and/or poly(vinyl pyrrolidone) (PVP), on the main features of the dried product using a 1,2-dipalmitoyl-sn-glycero-...
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Preserving the Integrity of Liposomes Prepared by Ethanol Injection upon Freeze-Drying: Insights from Combined Molecular Dynamics Simulations and Experimental Data
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TN_cdi_doaj_primary_oai_doaj_org_article_526491c5525a4f67a788f21c2dc3b808
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_526491c5525a4f67a788f21c2dc3b808
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ISSN
1999-4923
E-ISSN
1999-4923
DOI
10.3390/pharmaceutics12060530
