Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immu...
Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immunotherapy
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Publisher
United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Hydrophobic neoantigens are more immunogenic because they are better presented by the major histocompatibility complex and better recognized by T cells. Tumor cells can evade the immune response by expressing checkpoints such as programmed death ligand 1. Checkpoint blockade reactivates immune recognition and can be effective in diseases such as me...
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Full title
Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immunotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_5273824955bb4e9c9ad1db9c769fbc15
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5273824955bb4e9c9ad1db9c769fbc15
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ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1002/1878-0261.12748
