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Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm

Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5299a3c7a08b44bc9f3ec95e8cfcad72

Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm

About this item

Full title

Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-09, Vol.14 (1), p.5395-5395, Article 5395

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The reaction of CO
2
with H
2
O to form bicarbonate (HCO
3

) and H
+
controls sperm motility and fertilization via HCO
3

-stimulated cAMP synthesis. A complex network of signaling proteins participates in this reaction. Here, we identify key players that regulate intracellular pH (pH
i
) and HCO
3

Alternative Titles

Full title

Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5299a3c7a08b44bc9f3ec95e8cfcad72

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5299a3c7a08b44bc9f3ec95e8cfcad72

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-40855-0

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