T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subc...
T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1
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Author / Creator
He, Yujiao , Yang, Zhiguo , Zhao, Chen-si , Xiao, Zhihui , Gong, Yu , Li, Yun-Yi , Chen, Yiqi , Du, Yunting , Feng, Dianying , Altman, Amnon and Li, Yingqiu
Publisher
Cambridge: eLife Sciences Publications Ltd
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Language
English
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Cambridge: eLife Sciences Publications Ltd
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Contents
The nuclear pore complex (NPC) is the sole and selective gateway for nuclear transport, and its dysfunction has been associated with many diseases. The metazoan NPC subcomplex RanBP2, which consists of RanBP2 (Nup358), RanGAP1-SUMO1, and Ubc9, regulates the assembly and function of the NPC. The roles of immune signaling in regulation of NPC remain...
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Full title
T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1
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TN_cdi_doaj_primary_oai_doaj_org_article_52a195dd8ec34d5899bfc4bfb33f8a3f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52a195dd8ec34d5899bfc4bfb33f8a3f
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.67123
