Isolation of a novel human prion strain from a PRNP codon 129 heterozygous vCJD patient
Isolation of a novel human prion strain from a PRNP codon 129 heterozygous vCJD patient
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The epizootic prion disease of cattle, bovine spongiform encephalopathy (BSE), caused variant Creutzfeldt-Jakob disease (vCJD) in humans following dietary exposure. Codon 129 polymorphism of the human prion protein gene (PRNP), encoding either methionine (M) or valine (V), dictates the propagation of distinct human prion strains and up to now all b...
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Isolation of a novel human prion strain from a PRNP codon 129 heterozygous vCJD patient
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TN_cdi_doaj_primary_oai_doaj_org_article_52b691e35001456fb1c15d21b1dd2d7c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52b691e35001456fb1c15d21b1dd2d7c
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1012904
