The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis
The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis
About this item
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Author / Creator
Lin, Zhi , Liu, Jiao , Long, Fei , Kang, Rui , Kroemer, Guido , Tang, Daolin and Yang, Minghua
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Ferroptosis is a type of regulated necrosis caused by unrestricted lipid peroxidation and subsequent plasma membrane rupture. However, the lipid remodeling mechanism that determines sensitivity to ferroptosis remains poorly understood. Here, we report a previously unrecognized role for the lipid flippase solute carrier family 47 member 1 (SLC47A1)...
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Full title
The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis
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TN_cdi_doaj_primary_oai_doaj_org_article_52e485c9ab744d67a463bf5bd69ab0a4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52e485c9ab744d67a463bf5bd69ab0a4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-35707-2
