The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recrui...
The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1
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England: BioMed Central
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English
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England: BioMed Central
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Our previous genome-wide association study using the MA.27 aromatase inhibitors adjuvant trial identified SNPs in the long noncoding RNA MIR2052HG associated with breast cancer-free interval. MIR2052HG maintained ERα both by promoting AKT/FOXO3-mediated ESR1 transcription and by limiting ubiquitin-mediated ERα degradation. Our goal was to further e...
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The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1
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TN_cdi_doaj_primary_oai_doaj_org_article_52f2344848ac4558b1a49368d1c7aa8e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52f2344848ac4558b1a49368d1c7aa8e
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ISSN
1465-542X,1465-5411
E-ISSN
1465-542X
DOI
10.1186/s13058-019-1130-3
