The c-Rel transcription factor limits early interferon and neuroinflammatory responses to prevent he...
The c-Rel transcription factor limits early interferon and neuroinflammatory responses to prevent herpes simplex encephalitis onset in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Herpes simplex virus type 1 (HSV-1) is the predominant cause of herpes simplex encephalitis (HSE), a condition characterized by acute inflammation and viral replication in the brain. Host genetics contribute to HSE onset, including monogenic defects in type I interferon signaling in cases of childhood HSE. Mouse models suggest a further contributio...
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The c-Rel transcription factor limits early interferon and neuroinflammatory responses to prevent herpes simplex encephalitis onset in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_530179aba5094040854f2b4cc79fde4f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_530179aba5094040854f2b4cc79fde4f
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-00391-7
