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Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill pat...

Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill pat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5318687ea46e41f19a6b37062592e64e

Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill patients with normal or decreased renal function using Monte Carlo simulation

About this item

Full title

Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill patients with normal or decreased renal function using Monte Carlo simulation

Publisher

England: BioMed Central Ltd

Journal title

BMC infectious diseases, 2021-03, Vol.21 (1), p.307-11, Article 307

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Limited clinical studies describe the pharmacodynamics of fosfomycin (FOS), tigecycline (TGC) and colistin methanesulfonate (CMS) in combination against KPC-producing Klebsiella pneumoniae (KPC-Kp). Population pharmacokinetic models were used in our study. Monte Carlo simulation was conducted to calculate probability of target attainment (PTA) and...

Alternative Titles

Full title

Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill patients with normal or decreased renal function using Monte Carlo simulation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5318687ea46e41f19a6b37062592e64e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5318687ea46e41f19a6b37062592e64e

Other Identifiers

ISSN

1471-2334

E-ISSN

1471-2334

DOI

10.1186/s12879-021-06000-2

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