Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill pat...
Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill patients with normal or decreased renal function using Monte Carlo simulation
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Author / Creator
Wang, Guoan , Yu, Wei , Cui, Yushan , Shi, Qingyi , Huang, Chen and Xiao, Yonghong
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Limited clinical studies describe the pharmacodynamics of fosfomycin (FOS), tigecycline (TGC) and colistin methanesulfonate (CMS) in combination against KPC-producing Klebsiella pneumoniae (KPC-Kp). Population pharmacokinetic models were used in our study. Monte Carlo simulation was conducted to calculate probability of target attainment (PTA) and...
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Full title
Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill patients with normal or decreased renal function using Monte Carlo simulation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5318687ea46e41f19a6b37062592e64e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5318687ea46e41f19a6b37062592e64e
Other Identifiers
ISSN
1471-2334
E-ISSN
1471-2334
DOI
10.1186/s12879-021-06000-2