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An exposure‐response analysis of ponesimod clinical efficacy in a randomized phase III study in pati...

An exposure‐response analysis of ponesimod clinical efficacy in a randomized phase III study in pati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_531afc9bc7ca4e63b7b43fe2aa37c10f

An exposure‐response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosis

About this item

Full title

An exposure‐response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosis

Publisher

Hoboken: John Wiley & Sons, Inc

Journal title

CPT: Pharmacometrics & Systems Pharmacology, 2022-10, Vol.11 (10), p.1294-1304

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The efficacy of ponesimod and teriflunomide for the treatment of relapsing multiple sclerosis (MS) was compared in a randomized phase III trial. This study explores the exposure‐response (E‐R) relationships of efficacy end points (annualized relapse rate [ARR] and combined unique active lesions [CUALs]) of ponesimod observed in this trial. The E‐R...

Alternative Titles

Full title

An exposure‐response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_531afc9bc7ca4e63b7b43fe2aa37c10f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_531afc9bc7ca4e63b7b43fe2aa37c10f

Other Identifiers

ISSN

2163-8306

E-ISSN

2163-8306

DOI

10.1002/psp4.12778

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