Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinoma...
Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas
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Author / Creator
Wang, Jingshu , Zou, Kun , Feng, Xu , Chen, Miao , Li, Cong , Tang, Ranran , Xuan, Yang , Luo, Meihua , Chen, Wangbing , Qiu, Huijuan , Qin, Ge , Li, Yixin , Zhang, Changlin , Xiao, Binyi , Kang, Lan , Kang, Tiebang , Huang, Wenlin , Yu, Xinfa , Wu, Xiaojun and Deng, Wuguo
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
N-myc (and STAT) interactor (NMI) plays vital roles in tumor growth, progression, and metastasis. In this study, we identified NMI as a potential tumor suppressor in lung cancer and explored its molecular mechanism involved in lung cancer progression.
Human lung cancer cell lines and a mouse xenograft model was used to study the effect of NMI on...
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Full title
Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas
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TN_cdi_doaj_primary_oai_doaj_org_article_537ad2710bbb4ea1a1048a099c633a8c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_537ad2710bbb4ea1a1048a099c633a8c
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-017-0705-9