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Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflamm...

Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflamm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_538094955b874388ace1e053acd30f22

Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease

About this item

Full title

Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-03, Vol.12 (1), p.1869-15, Article 1869

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ulcerative colitis and Crohn’s disease are forms of inflammatory bowel disease whose incidence and prevalence are increasing worldwide. These diseases lead to chronic inflammation of the gastrointestinal tract as a result of an abnormal response of the immune system. Recent studies positioned Cortistatin, which shows low stability in plasma, as a c...

Alternative Titles

Full title

Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_538094955b874388ace1e053acd30f22

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_538094955b874388ace1e053acd30f22

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-22076-5

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