Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflamm...
Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Ulcerative colitis and Crohn’s disease are forms of inflammatory bowel disease whose incidence and prevalence are increasing worldwide. These diseases lead to chronic inflammation of the gastrointestinal tract as a result of an abnormal response of the immune system. Recent studies positioned Cortistatin, which shows low stability in plasma, as a c...
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Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease
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TN_cdi_doaj_primary_oai_doaj_org_article_538094955b874388ace1e053acd30f22
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_538094955b874388ace1e053acd30f22
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22076-5