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Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen

Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_539421cdbf2649ba84e049f00249ee1a

Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen

About this item

Full title

Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-06, Vol.11 (1), p.2908-2908, Article 2908

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Adoptive cell therapy (ACT) with tumor-specific T cells can mediate cancer regression. The main target of tumor-specific T cells are neoantigens arising from mutations in self-proteins. Although the majority of cancer neoantigens are unique to each patient, and therefore not broadly useful for ACT, some are shared. We studied oligoclonal T-cell rec...

Alternative Titles

Full title

Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_539421cdbf2649ba84e049f00249ee1a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_539421cdbf2649ba84e049f00249ee1a

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-16755-y

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