Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen
Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Adoptive cell therapy (ACT) with tumor-specific T cells can mediate cancer regression. The main target of tumor-specific T cells are neoantigens arising from mutations in self-proteins. Although the majority of cancer neoantigens are unique to each patient, and therefore not broadly useful for ACT, some are shared. We studied oligoclonal T-cell rec...
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Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen
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TN_cdi_doaj_primary_oai_doaj_org_article_539421cdbf2649ba84e049f00249ee1a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_539421cdbf2649ba84e049f00249ee1a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16755-y