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ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-...

ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_53a9c953bbc94225b8450f598b31a197

ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation

About this item

Full title

ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation

Publisher

London: Nature Publishing Group UK

Journal title

Translational psychiatry, 2020-11, Vol.10 (1), p.406-406, Article 406

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Adenosine, its interacting A
1
and A
2A
receptors, and particularly the variant rs5751876 in the A
2A
gene
ADORA2A
have been shown to modulate anxiety, arousal, and sleep. In a pilot positron emission tomography (PET) study in healthy male subjects, we suggested an effect of rs5751876 on in vivo brain A
1
receptor (A

Alternative Titles

Full title

ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_53a9c953bbc94225b8450f598b31a197

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_53a9c953bbc94225b8450f598b31a197

Other Identifiers

ISSN

2158-3188

E-ISSN

2158-3188

DOI

10.1038/s41398-020-01085-w

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