Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oes...
Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands
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Author / Creator
Owen, Richard Peter , White, Michael Joseph , Severson, David Tyler , Braden, Barbara , Bailey, Adam , Goldin, Robert , Wang, Lai Mun , Ruiz-Puig, Carlos , Maynard, Nicholas David , Green, Angie , Piazza, Paolo , Buck, David , Middleton, Mark Ross , Ponting, Chris Paul , Schuster-Böckler, Benjamin and Lu, Xin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Barrett’s oesophagus is a precursor of oesophageal adenocarcinoma. In this common condition, squamous epithelium in the oesophagus is replaced by columnar epithelium in response to acid reflux. Barrett’s oesophagus is highly heterogeneous and its relationships to normal tissues are unclear. Here we investigate the cellular complexity of Barrett’s o...
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Full title
Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_53c87fc54c1542f789eced6b76559b59
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_53c87fc54c1542f789eced6b76559b59
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06796-9
