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Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma osci...

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma osci...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5419a7301c0c4759a27e32681a06af3c

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer's disease

About this item

Full title

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer's disease

Publisher

England: BioMed Central Ltd

Journal title

Translational Neurodegeneration, 2023-02, Vol.12 (1), p.6-6, Article 6

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Alzheimer's disease (AD) is a progressive multifaceted neurodegenerative disorder for which no disease-modifying treatment exists. Neuroinflammation is central to the pathology progression, with evidence suggesting that microglia-released galectin-3 (gal3) plays a pivotal role by amplifying neuroinflammation in AD. However, the possible involvement...

Alternative Titles

Full title

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5419a7301c0c4759a27e32681a06af3c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5419a7301c0c4759a27e32681a06af3c

Other Identifiers

ISSN

2047-9158

E-ISSN

2047-9158

DOI

10.1186/s40035-023-00338-0