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Synthetic mRNAs Containing Minimalistic Untranslated Regions Are Highly Functional In Vitro and In V...

Synthetic mRNAs Containing Minimalistic Untranslated Regions Are Highly Functional In Vitro and In V...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5431fc445dd74b9097329e29d690d397

Synthetic mRNAs Containing Minimalistic Untranslated Regions Are Highly Functional In Vitro and In Vivo

About this item

Full title

Synthetic mRNAs Containing Minimalistic Untranslated Regions Are Highly Functional In Vitro and In Vivo

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2024-08, Vol.13 (15), p.1242

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Synthetic mRNA produced by in vitro transcription (ivt mRNA) is the active pharmaceutical ingredient of approved anti-COVID-19 vaccines and of many drugs under development. Such synthetic mRNA typically contains several hundred bases of non-coding "untranslated" regions (UTRs) that are involved in the stabilization and translation of the mRNA. Howe...

Alternative Titles

Full title

Synthetic mRNAs Containing Minimalistic Untranslated Regions Are Highly Functional In Vitro and In Vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5431fc445dd74b9097329e29d690d397

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5431fc445dd74b9097329e29d690d397

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells13151242

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