Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation
Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
The innervation of the inner ear critically depends on the two neurotrophins Ntf3 and Bdnf. In contrast to this molecularly well-established dependency, evidence regarding the need of innervation for long-term maintenance of inner ear hair cells is inconclusive, due to experimental variability. Mutant mice that lack both neurotrophins could shed li...
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Full title
Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation
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TN_cdi_doaj_primary_oai_doaj_org_article_54ac0654c27141ff963b9a9ba6599b65
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54ac0654c27141ff963b9a9ba6599b65
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2015.00033
