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Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altere...

Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altere...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54d8ba5ed19745f68237d1d74ca99a08

Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer

About this item

Full title

Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-11, Vol.13 (1), p.20223-20223, Article 20223

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Several alterations in fibroblast growth factor receptor (FGFR) genes have been found in breast cancer; however, they have not been well characterized as therapeutic targets. Futibatinib (TAS-120; Taiho) is a novel, selective, pan-FGFR inhibitor that inhibits FGFR1-4 at nanomolar concentrations. We sought to determine futibatinib’s efficacy in brea...

Alternative Titles

Full title

Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_54d8ba5ed19745f68237d1d74ca99a08

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54d8ba5ed19745f68237d1d74ca99a08

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-46586-y

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