Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altere...
Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Several alterations in fibroblast growth factor receptor (FGFR) genes have been found in breast cancer; however, they have not been well characterized as therapeutic targets. Futibatinib (TAS-120; Taiho) is a novel, selective, pan-FGFR inhibitor that inhibits FGFR1-4 at nanomolar concentrations. We sought to determine futibatinib’s efficacy in brea...
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Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_54d8ba5ed19745f68237d1d74ca99a08
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54d8ba5ed19745f68237d1d74ca99a08
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-46586-y