Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition
Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition
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Author / Creator
Jungwirth, Jiri , Urbanova, Marketa , Boot, Arnoud , Hosek, Petr , Bendova, Petra , Siskova, Anna , Svec, Jiri , Kment, Milan , Tumova, Daniela , Summerova, Sandra , Benes, Zdenek , Buchler, Tomas , Kohout, Pavel , Hucl, Tomas , Matej, Radoslav , Vodickova, Ludmila , van Wezel, Tom , Vodicka, Pavel and Vymetalkova, Veronika
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A large proportion of colorectal carcinomas (CRC) evolve from colorectal adenomas. However, not all individuals with colonic adenomas have a risk of CRC substantially higher than those of the general population. The aim of the study was to determine the differences or similarities of mutation profile among low- and high-grade adenomas and in situ c...
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Full title
Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition
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TN_cdi_doaj_primary_oai_doaj_org_article_54f63a23fe0d4103be421dd216104f70
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54f63a23fe0d4103be421dd216104f70
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-06498-9
