Atorvastatin does not protect against ischemia-reperfusion damage in cholestatic rat livers
Atorvastatin does not protect against ischemia-reperfusion damage in cholestatic rat livers
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Extrahepatic cholestasis sensitizes the liver to ischemia/reperfusion (I/R) injury during surgery for perihilar cholangiocarcinoma. It is associated with pre-existent sterile inflammation, microvascular perfusion defects, and impaired energy status. Statins have been shown to protect against I/R injury in normal and steatotic mouse livers. Therefor...
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Full title
Atorvastatin does not protect against ischemia-reperfusion damage in cholestatic rat livers
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TN_cdi_doaj_primary_oai_doaj_org_article_54fec2f126354fea92f73fafb561d27d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_54fec2f126354fea92f73fafb561d27d
Other Identifiers
ISSN
1471-2482
E-ISSN
1471-2482
DOI
10.1186/s12893-017-0235-9
