A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and...
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans
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Author / Creator
Faculty of Medicine , Medicinska fakulteten , Department of Experimental Medical Science , Lund University , Institutionen för experimentell medicinsk vetenskap , Diabetes - Islet Cell Exocytosis , Institutionen för kliniska vetenskaper, Malmö , Lunds universitet , Diabetes - öcellsexocytos , Department of Clinical Sciences, Malmö , MacDonald, Patrick E , De Marinis, Yang Zhang , Ramracheya, Reshma , Salehi, Albert , Ma, Xiaosong , Johnson, Paul R V , Cox, Roger , Eliasson, Lena and Rorsman, Patrik
Publisher
United States: Public Library of Science (PLoS)
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science (PLoS)
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Scope and Contents
Contents
Glucagon, secreted from pancreatic islet alpha cells, stimulates gluconeogenesis and liver glycogen breakdown. The mechanism regulating glucagon release is debated, and variously attributed to neuronal control, paracrine control by neighbouring beta cells, or to an intrinsic glucose sensing by the alpha cells themselves. We examined hormone secreti...
Alternative Titles
Full title
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans
Authors, Artists and Contributors
Author / Creator
Medicinska fakulteten
Department of Experimental Medical Science
Lund University
Institutionen för experimentell medicinsk vetenskap
Diabetes - Islet Cell Exocytosis
Institutionen för kliniska vetenskaper, Malmö
Lunds universitet
Diabetes - öcellsexocytos
Department of Clinical Sciences, Malmö
MacDonald, Patrick E
De Marinis, Yang Zhang
Ramracheya, Reshma
Salehi, Albert
Ma, Xiaosong
Johnson, Paul R V
Cox, Roger
Eliasson, Lena
Rorsman, Patrik
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_550e7928dd0b4329acb85a04cd4d16ab
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_550e7928dd0b4329acb85a04cd4d16ab
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.0050143
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