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A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and...

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_550e7928dd0b4329acb85a04cd4d16ab

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans

About this item

Full title

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans

Publisher

United States: Public Library of Science (PLoS)

Journal title

PLoS biology, 2007-06, Vol.5 (6), p.e143

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science (PLoS)

More information

Scope and Contents

Contents

Glucagon, secreted from pancreatic islet alpha cells, stimulates gluconeogenesis and liver glycogen breakdown. The mechanism regulating glucagon release is debated, and variously attributed to neuronal control, paracrine control by neighbouring beta cells, or to an intrinsic glucose sensing by the alpha cells themselves. We examined hormone secreti...

Alternative Titles

Full title

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_550e7928dd0b4329acb85a04cd4d16ab

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_550e7928dd0b4329acb85a04cd4d16ab

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.0050143

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