Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics
Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
FOXO transcription factors regulate cellular homeostasis, longevity and response to stress. FOXO1 (also known as FKHR) is a key regulator of hepatic glucose production and lipid metabolism, and its specific inhibition may have beneficial effects on diabetic hyperglycemia by reducing hepatic glucose production. Moreover, all FOXO proteins are consid...
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Full title
Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics
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TN_cdi_doaj_primary_oai_doaj_org_article_5535b5d8c825421d95d204de33775efd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5535b5d8c825421d95d204de33775efd
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells8090966
