Non-small cell lung cancer sensitisation to platinum chemotherapy via new thiazole-triazole hybrids...
Non-small cell lung cancer sensitisation to platinum chemotherapy via new thiazole-triazole hybrids acting as dual T-type CCB/MMP-9 inhibitors
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England: Taylor & Francis Ltd
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Language
English
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Publisher
England: Taylor & Francis Ltd
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Contents
Cisplatin remains the unchallenged standard therapy for NSCLC. However, it is not completely curative due to drug resistance and oxidative stress-induced toxicity. Drug resistance is linked to overexpression of matrix metalloproteinases (MMPs) and aberrant calcium signalling. We report synthesis of novel thiazole-triazole hybrids as MMP-9 inhibitor...
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Non-small cell lung cancer sensitisation to platinum chemotherapy via new thiazole-triazole hybrids acting as dual T-type CCB/MMP-9 inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_5539ecc082aa403a859e84b2104d936f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5539ecc082aa403a859e84b2104d936f
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ISSN
1475-6366,1475-6374
E-ISSN
1475-6374
DOI
10.1080/14756366.2024.2388209
