Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta olig...
Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Adult hippocampal neurogenesis plays an important role in synaptic plasticity and cogntive function. We reported that higher numbers of neural stem cells (NSC) in the hippocampus of cognitively-intact individuals with high Alzheimer's disease (AD) pathology (plaques and tangles) is associated with decreased synaptic amyloid beta oligomers (Aβο), an...
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Full title
Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes
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TN_cdi_doaj_primary_oai_doaj_org_article_558165347ed14f368a584933fe424384
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_558165347ed14f368a584933fe424384
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-019-0322-8
