Imputation of ancient human genomes
Imputation of ancient human genomes
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Author / Creator
Sousa da Mota, Bárbara , Rubinacci, Simone , Cruz Dávalos, Diana Ivette , G. Amorim, Carlos Eduardo , Sikora, Martin , Johannsen, Niels N. , Szmyt, Marzena H. , Włodarczak, Piotr , Szczepanek, Anita , Przybyła, Marcin M. , Schroeder, Hannes , Allentoft, Morten E. , Willerslev, Eske , Malaspinas, Anna-Sapfo and Delaneau, Olivier
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Due to
postmortem
DNA degradation and microbial colonization, most ancient genomes have low depth of coverage, hindering genotype calling. Genotype imputation can improve genotyping accuracy for low-coverage genomes. However, it is unknown how accurate ancient DNA imputation is and whether imputation introduces bias to downstream analyses. He...
Alternative Titles
Full title
Imputation of ancient human genomes
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_558971cda6864dd59a519463d4cccb3c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_558971cda6864dd59a519463d4cccb3c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39202-0