Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution
Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution
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Author / Creator
Küçükoğlu, Berk , Mohammed, Inayathulla , Guerrero-Ferreira, Ricardo C. , Ribet, Stephanie M. , Varnavides, Georgios , Leidl, Max Leo , Lau, Kelvin , Nazarov, Sergey , Myasnikov, Alexander , Kube, Massimo , Radecke, Julika , Sachse, Carsten , Müller-Caspary, Knut , Ophus, Colin and Stahlberg, Henning
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Cryo-transmission electron microscopy (cryo-EM) of frozen hydrated specimens is an efficient method for the structural analysis of purified biological molecules. However, cryo-EM and cryo-electron tomography are limited by the low signal-to-noise ratio (SNR) of recorded images, making detection of smaller particles challenging. For dose-resilient s...
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Full title
Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution
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TN_cdi_doaj_primary_oai_doaj_org_article_561d8052cab546c7bd91c70e0853b4c4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_561d8052cab546c7bd91c70e0853b4c4
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52403-5
