A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circu...
A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Within a cell, synthetic and native genes compete for expression machinery, influencing cellular process dynamics through resource couplings. Models that simplify competitive resource binding kinetics can guide the design of strategies for countering these couplings. However, in bacteria resource availability and cell growth rate are interlinked, w...
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A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits
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TN_cdi_doaj_primary_oai_doaj_org_article_56416716262e4fb1886e1f20ed8d1186
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_56416716262e4fb1886e1f20ed8d1186
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-46410-9
