Mechanism of membrane-curvature generation by ER-tubule shaping proteins
Mechanism of membrane-curvature generation by ER-tubule shaping proteins
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The endoplasmic reticulum (ER) network consists of tubules with high membrane curvature in cross-section, generated by the reticulons and REEPs. These proteins have two pairs of trans-membrane (TM) segments, followed by an amphipathic helix (APH), but how they induce curvature is poorly understood. Here, we show that REEPs form homodimers by intera...
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Mechanism of membrane-curvature generation by ER-tubule shaping proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_56438c7966b446978619a8f0309f5673
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_56438c7966b446978619a8f0309f5673
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20625-y
