The effect of intracerebroventricular administration of orexin receptor type 2 antagonist on pentyle...
The effect of intracerebroventricular administration of orexin receptor type 2 antagonist on pentylenetetrazol-induced kindled seizures and anxiety in rats
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Current antiepileptic drugs are not able to prevent recurrent seizures in all patients. Orexins are excitatory hypothalamic neuropeptides that their receptors (Orx1R and Orx2R) are found almost in all major regions of the brain. Pentylenetetrazol (PTZ)-induced kindling is a known experimental model for epileptic seizures. The purpose of this study...
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Full title
The effect of intracerebroventricular administration of orexin receptor type 2 antagonist on pentylenetetrazol-induced kindled seizures and anxiety in rats
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TN_cdi_doaj_primary_oai_doaj_org_article_565429dd2b6e431c8ba92383162cf9a2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_565429dd2b6e431c8ba92383162cf9a2
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ISSN
1471-2202
E-ISSN
1471-2202
DOI
10.1186/s12868-018-0445-9
