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Protective effects of tumor necrosis factor-α blockade by adalimumab on articular cartilage and subc...

Protective effects of tumor necrosis factor-α blockade by adalimumab on articular cartilage and subc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5671744a218646908b430120e93ae94f

Protective effects of tumor necrosis factor-α blockade by adalimumab on articular cartilage and subchondral bone in a rat model of osteoarthritis

About this item

Full title

Protective effects of tumor necrosis factor-α blockade by adalimumab on articular cartilage and subchondral bone in a rat model of osteoarthritis

Publisher

Brazil: Associação Brasileira de Divulgação Científica

Journal title

Brazilian journal of medical and biological research, 2015-10, Vol.48 (10), p.863-870

Language

English

Formats

Publication information

Publisher

Brazil: Associação Brasileira de Divulgação Científica

More information

Scope and Contents

Contents

We aimed to investigate the effects of an anti-tumor necrosis factor-α antibody (ATNF) on cartilage and subchondral bone in a rat model of osteoarthritis. Twenty-four rats were randomly divided into three groups: sham-operated group (n=8); anterior cruciate ligament transection (ACLT)+normal saline (NS) group (n=8); and ACLT+ATNF group (n=8). The r...

Alternative Titles

Full title

Protective effects of tumor necrosis factor-α blockade by adalimumab on articular cartilage and subchondral bone in a rat model of osteoarthritis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5671744a218646908b430120e93ae94f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5671744a218646908b430120e93ae94f

Other Identifiers

ISSN

0100-879X

E-ISSN

1414-431X

DOI

10.1590/1414-431X20154407

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