Interferon lambda protects the female reproductive tract against Zika virus infection
Interferon lambda protects the female reproductive tract against Zika virus infection
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Although Zika virus (ZIKV) can be transmitted sexually and cause congenital birth defects, immune control mechanisms in the female reproductive tract (FRT) are not well characterized. Here we show that treatment of primary human vaginal and cervical epithelial cells with interferon (IFN)-α/β or IFN-λ induces host defense transcriptional signatures...
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Full title
Interferon lambda protects the female reproductive tract against Zika virus infection
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TN_cdi_doaj_primary_oai_doaj_org_article_568be70d5e744aafb4350b13e5aaa00d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_568be70d5e744aafb4350b13e5aaa00d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07993-2
