Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility
Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mammalian fertilisation begins when sperm interacts with the egg zona pellucida (ZP), whose ZP1 subunit is important for fertility by covalently cross-linking ZP filaments into a three-dimensional matrix. Like ZP4, a structurally-related component absent in the mouse, ZP1 is predicted to contain an N-terminal ZP-N domain of unknown function. Here w...
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Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility
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TN_cdi_doaj_primary_oai_doaj_org_article_56d66a23508b4bf9b30688e79a38ded7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_56d66a23508b4bf9b30688e79a38ded7
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10931-5
