Pipeline for development of acylated peptide based CGRP receptor antagonist with extended half-life...
Pipeline for development of acylated peptide based CGRP receptor antagonist with extended half-life for migraine treatment
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Migraine is a debilitating headache disorder. The disease has neurovascular origin and migraine attacks can be elicited by vasodilative neuropeptides such as alpha calcitonin gene-related peptide (αCGRP). Antagonizing CGRP actions in migraine patients has proven clinically efficient. Here, we present a pipeline for development of a peptide-based hC...
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Full title
Pipeline for development of acylated peptide based CGRP receptor antagonist with extended half-life for migraine treatment
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TN_cdi_doaj_primary_oai_doaj_org_article_56ec284cf0144f279fbe06f0f44442c9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_56ec284cf0144f279fbe06f0f44442c9
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-84547-1
