Loss of myosin light chain kinase induces the cellular senescence associated secretory phenotype to...
Loss of myosin light chain kinase induces the cellular senescence associated secretory phenotype to promote breast epithelial cell migration
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Overexpression or activation of oncogenes or loss of tumor-suppressor genes can induce cellular senescence as a defense mechanism against tumor development, thereby maintaining cellular homeostasis. However, cancer cells can circumvent this senescent state and continue to spread. Myosin light chain kinase (MLCK) is downregulated in many breast canc...
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Loss of myosin light chain kinase induces the cellular senescence associated secretory phenotype to promote breast epithelial cell migration
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TN_cdi_doaj_primary_oai_doaj_org_article_56fbeca6658f458ab0ef871f85a4091e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_56fbeca6658f458ab0ef871f85a4091e
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2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-76868-y