Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection
Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The genomes of HIV-2 and some SIV strains contain the accessory gene vpx, which carries out several functions during infection, including the downregulation of SAMHD1. Vpx is also commonly used in experiments to increase HIV-1 infection efficiency in myeloid cells, particularly in studies that investigate the activation of antiviral pathways. Howev...
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Full title
Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection
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TN_cdi_doaj_primary_oai_doaj_org_article_5710cfeed3474dbcba859ca5edfb2a2e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5710cfeed3474dbcba859ca5edfb2a2e
Other Identifiers
ISSN
1742-4690
E-ISSN
1742-4690
DOI
10.1186/s12977-021-00548-2
