IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer
IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Contact sites of endoplasmic reticulum (ER) and mitochondria locally convey calcium signals between the IP
3
receptors (IP3R) and the mitochondrial calcium uniporter, and are central to cell survival. It remains unclear whether IP3Rs also have a structural role in contact formation and whether the different IP3R isoforms have redundant functi...
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IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer
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TN_cdi_doaj_primary_oai_doaj_org_article_573c9a6e3c934f97817996bbe29c011b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_573c9a6e3c934f97817996bbe29c011b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11646-3