Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in l...
Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in living cells
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Tau is a microtubule-associated protein that is regulated by post-translational modifications. The most studied of these modifications is phosphorylation, which affects Tau’s aggregation and loss- and gain-of-functions, including the interaction with microtubules, in Alzheimer’s disease and primary tauopathies. However, little is known about how Ta...
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Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in living cells
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TN_cdi_doaj_primary_oai_doaj_org_article_5740702fac0f4501aea30acf98b8a9d9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5740702fac0f4501aea30acf98b8a9d9
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ISSN
1756-6606
E-ISSN
1756-6606
DOI
10.1186/s13041-024-01078-6