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Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in l...

Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in l...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5740702fac0f4501aea30acf98b8a9d9

Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in living cells

About this item

Full title

Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in living cells

Publisher

England: BioMed Central Ltd

Journal title

Molecular brain, 2024-02, Vol.17 (1), p.7-7, Article 7

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Tau is a microtubule-associated protein that is regulated by post-translational modifications. The most studied of these modifications is phosphorylation, which affects Tau’s aggregation and loss- and gain-of-functions, including the interaction with microtubules, in Alzheimer’s disease and primary tauopathies. However, little is known about how Ta...

Alternative Titles

Full title

Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in living cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5740702fac0f4501aea30acf98b8a9d9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5740702fac0f4501aea30acf98b8a9d9

Other Identifiers

ISSN

1756-6606

E-ISSN

1756-6606

DOI

10.1186/s13041-024-01078-6

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