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Tyrosinase in melanoma inhibits anti-tumor activity of PD-1 deficient T cells

Tyrosinase in melanoma inhibits anti-tumor activity of PD-1 deficient T cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_57a390581f384f18b579a4f7027bd03b

Tyrosinase in melanoma inhibits anti-tumor activity of PD-1 deficient T cells

About this item

Full title

Tyrosinase in melanoma inhibits anti-tumor activity of PD-1 deficient T cells

Publisher

England: BioMed Central Ltd

Journal title

BMC biology, 2025-05, Vol.23 (1), p.135-15, Article 135

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Melanoma is one of the most commonly diagnosed malignancies and serves as a model for studying immunotherapy. The B16 melanoma model, resembling human cold tumors that lack T cell infiltration and show minimal response to PD-1 blockade, is widely used for studying melanoma and its resistance to immunotherapy. Therefore, understanding the molecular...

Alternative Titles

Full title

Tyrosinase in melanoma inhibits anti-tumor activity of PD-1 deficient T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_57a390581f384f18b579a4f7027bd03b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_57a390581f384f18b579a4f7027bd03b

Other Identifiers

ISSN

1741-7007

E-ISSN

1741-7007

DOI

10.1186/s12915-025-02237-4

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