MMP9 integrates multiple immunoregulatory pathways that discriminate high suppressive activity of hu...
MMP9 integrates multiple immunoregulatory pathways that discriminate high suppressive activity of human mesenchymal stem cells
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The mechanisms underlying mesenchymal stem cells’ (MSC) suppressive potency are largely unknown. We here show that highly suppressive human adipose tissue-derived MSC (AdMSC) display and induce a differential immunologic profile, upon ongoing AdMSC suppressive activity, promoting: (i) early correlated inhibition of IFN-γ and TNF-α production, along...
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Full title
MMP9 integrates multiple immunoregulatory pathways that discriminate high suppressive activity of human mesenchymal stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_580b000eb41d4ca581e73640fbe8af80
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_580b000eb41d4ca581e73640fbe8af80
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-00923-0
