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A brain proteomic investigation of rapamycin effects in the Tsc1 +/− mouse model

A brain proteomic investigation of rapamycin effects in the Tsc1 +/− mouse model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_586a03b0e6734851afec92d2ab0bc9c8

A brain proteomic investigation of rapamycin effects in the Tsc1 +/− mouse model

About this item

Full title

A brain proteomic investigation of rapamycin effects in the Tsc1 +/− mouse model

Publisher

England: BioMed Central Ltd

Journal title

Molecular autism, 2017-08, Vol.8 (1), p.41-41, Article 41

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Tuberous sclerosis complex (TSC) is a rare monogenic disorder characterized by benign tumors in multiple organs as well as a high prevalence of epilepsy, intellectual disability and autism. TSC is caused by inactivating mutations in the
or
genes. Heterozygocity induces hyperactivation of mTOR which can be inhibited by mTOR inhibitors, such as...

Alternative Titles

Full title

A brain proteomic investigation of rapamycin effects in the Tsc1 +/− mouse model

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_586a03b0e6734851afec92d2ab0bc9c8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_586a03b0e6734851afec92d2ab0bc9c8

Other Identifiers

ISSN

2040-2392

E-ISSN

2040-2392

DOI

10.1186/s13229-017-0151-y

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