Association between Olaparib Exposure and Early Toxicity in BRCA-Mutated Ovarian Cancer Patients: Re...
Association between Olaparib Exposure and Early Toxicity in BRCA-Mutated Ovarian Cancer Patients: Results from a Retrospective Multicenter Study
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Author / Creator
Velev, Maud , Puszkiel, Alicja , Blanchet, Benoit , de Percin, Sixtine , Delanoy, Nicolas , Medioni, Jacques , Gervais, Claire , Balakirouchenane, David , Khoudour, Nihel , Pautier, Patricia , Leary, Alexandra , Ajgal, Zahra , Hirsch, Laure , Goldwasser, François , Alexandre, Jerome and Beinse, Guillaume
Publisher
Basel: MDPI AG
Journal title
Language
English
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Publisher
Basel: MDPI AG
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Contents
Factors associated with olaparib toxicity remain unknown in ovarian cancer patients. The large inter-individual variability in olaparib pharmacokinetics could contribute to the onset of early significant adverse events (SAE). We aimed to retrospectively analyze the pharmacokinetic/pharmacodynamic relationship for toxicity in ovarian cancer patients...
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Full title
Association between Olaparib Exposure and Early Toxicity in BRCA-Mutated Ovarian Cancer Patients: Results from a Retrospective Multicenter Study
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_58923e84ca98466e86ca7b10c494bf84
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_58923e84ca98466e86ca7b10c494bf84
Other Identifiers
ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph14080804
