Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43
Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Fatty acids belong to a group of compounds already acknowledged for their broad antiviral efficacy. However, little is yet known about their effect on replication of human coronaviruses. To shed light on this subject, we first screened 15 fatty acids, three lipid-soluble vitamins, and cholesterol, on SARS-CoV-2 RdRp, and identified the four fatty a...
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Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43
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TN_cdi_doaj_primary_oai_doaj_org_article_58a4f7ab06a84dedb6692d07851e02d4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_58a4f7ab06a84dedb6692d07851e02d4
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-23880-9
