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The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-defici...

The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-defici...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_58db20dd5da042619a92265d2181039b

The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-deficient hippocampal neurons

About this item

Full title

The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-deficient hippocampal neurons

Publisher

England: BioMed Central Ltd

Journal title

Molecular autism, 2019-11, Vol.10 (1), p.41-18, Article 41

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Although neuronal extracellular sensing is emerging as crucial for brain wiring and therefore plasticity, little is known about these processes in neurodevelopmental disorders. Ubiquitin protein ligase E3A (UBE3A) plays a key role in neurodevelopment. Lack of UBE3A leads to Angelman syndrome (AS), while its increase is among the most prevalent gene...

Alternative Titles

Full title

The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-deficient hippocampal neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_58db20dd5da042619a92265d2181039b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_58db20dd5da042619a92265d2181039b

Other Identifiers

ISSN

2040-2392

E-ISSN

2040-2392

DOI

10.1186/s13229-019-0293-1

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