Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer
Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extensive fibroinflammatory stroma and often experiences conditions of insufficient oxygen availability or hypoxia. Cancer-associated fibroblasts (CAF) are a predominant and heterogeneous population of stromal cells within the pancreatic tumor microenvironment. Here, we uncover a previo...
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Full title
Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_58ecf0cb5fb64401ae4dd519669818f1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_58ecf0cb5fb64401ae4dd519669818f1
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ISSN
2157-9024
E-ISSN
2157-9024
DOI
10.1038/s41389-022-00434-2
