HIF-1α participates in the regulation of S100A16-HRD1-GSK3β/CK1α pathway in renal hypoxia injury
HIF-1α participates in the regulation of S100A16-HRD1-GSK3β/CK1α pathway in renal hypoxia injury
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Han, Shuying , Jin, Runbing , Huo, Lei , Teng, Yunfei , Zhao, Lihua , Zhang, Kaini , Li, Rongfeng , Su, Dongming and Liang, Xiubin
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
S100 calcium-binding protein 16 (S100A16) is implicated in both chronic kidney disease (CKD) and acute kidney injury (AKI). Previous research has shown that S100A16 contributes to AKI by facilitating the ubiquitylation and degradation of glycogen synthase kinase 3β (GSK3β) and casein kinase 1α (CK1α) through the activation of HMG-CoA reductase degr...
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Full title
HIF-1α participates in the regulation of S100A16-HRD1-GSK3β/CK1α pathway in renal hypoxia injury
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TN_cdi_doaj_primary_oai_doaj_org_article_58f54d9439ea4bc1848aebaa374f2a9e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_58f54d9439ea4bc1848aebaa374f2a9e
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06696-5
