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Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephal...

Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_58f69881c3e94968a5c457db1a7af330

Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis

About this item

Full title

Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis

Publisher

London: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2022-11, Vol.19 (1), p.1-270, Article 270

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Background Cladribine is a synthetic purine analogue that interferes with DNA synthesis and repair next to disrupting cellular proliferation in actively dividing lymphocytes. The compound is approved for the treatment of multiple sclerosis (MS). Cladribine can cross the blood-brain barrier, suggesting a potential effect on central nervous system (C...

Alternative Titles

Full title

Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_58f69881c3e94968a5c457db1a7af330

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_58f69881c3e94968a5c457db1a7af330

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-022-02588-7

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